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JWH-018 (1-pentyl-3-(1-naphthoyl)indole) or AM-678 is an analgesic chemical from the naphthoylindole family that acts as a full agonist at both the CB1 and CB2 cannabinoid receptors,with some selectivity for CB2. It produces effects in animals similar to those of tetrahydrocannabinol (THC),a cannabinoid naturally present in cannabis, leading to its use in synthetic cannabis products that in some countries are sold legally as incense blends.